Fisetin

Appearance, Form & Color: Solid, Pale Yellow to Very Dark Yellow

Melting Point: >330 °C(lit.)

Boiling Point: 348.61°C (rough estimate)

Density: 1.2981 (rough estimate)

Refractive Index: 1.4413 (estimate)

Storage Temperature: Sealed in dry, Store in freezer, under -20°C

Solubility: DMSO (Slightly), Methanol (Slightly)

pKa: 6.83±0.40 (Predicted)

LogP: 1.970 (est)

Stability: Hygroscopic

Fisetin is primarily used as a research chemical and a precursor in drug synthesis, with specific applications in the following areas:

1. Laboratory Research and Analysis:

Content Determination and Identification: This product is directly used for content determination, identification, and pharmacological experiments in scientific research and analysis.

2. Drug Synthesis:

Active Precursor: As a naturally occurring therapeutically active flavonol, it is used for the synthesis of compounds with pharmaceutical activity, particularly anti-inflammatory, anticonvulsant, and antiproliferative drugs.

3. Pharmacological Efficacy Research (Based on animal and in vitro studies):

Prostaglandin Inhibition: It inhibits prostaglandin production in methylcholanthrene-transformed 3T3 mouse fibroblasts.

Enzyme Inhibition: It inhibits aldose reductase in rat eye lenses.

Neuroprotection and Cognitive Improvement: Animal experiments suggest it may help improve memory.