Magnesium L-threonate

Magnesium L-threonate, also known as Magnesium(2+) Ion Bis((2R,3S)-2,3,4-trihydroxybutanoate) or L-Threonic acid magnesium salt, is a high-purity (≥98%) white to off-white crystalline powder and the only magnesium compound clinically proven to significantly cross the blood-brain barrier, delivering magnesium directly into the brain where it is physiologically present as a metabolite of vitamin C. Unlike ordinary magnesium forms, it markedly increases cerebrospinal fluid magnesium concentration, preserves glutamatergic synaptic transmission under Alzheimer’s-like pathological conditions, promotes synaptic plasticity and long-term potentiation, and exerts broad neuroprotective effects that combat oxidative stress, support brain anti-aging, and restore cognitive function. This advanced research-grade and dietary supplement ingredient demonstrates multifaceted benefits including enhanced memory consolidation, learning ability, mood regulation, deep sleep improvement, alertness, energy levels, and daily productivity, with preclinical data further indicating potential neurofunctional support in ADHD, making Magnesium L-threonate the premier choice for high-performance formulations focused on cognitive enhancement, brain health optimization, and therapeutic innovation in neurodegenerative and age-related cognitive disorders.