Pyrroloquinoline quinone disodium salt
122628-50-6
Pyrroloquinoline quinone disodium salt
Pyrroloquinoline quinone disodium salt (PQQ-2Na) is a novel redox cofactor and an essential nutrient for mammals, primarily used as an active ingredient in health supplements to exert neuroprotective, immunomodulatory, and organ-protective health-supporting effects. Additionally, as a prosthetic group for enzymes, it participates in various catalytic reactions within living organisms.
개요
Pyrroloquinoline quinone disodium salt (PQQ-2Na) is the sodium salt derivative of pyrroloquinoline quinone (PQQ). PQQ is a novel prosthetic group (or new redox cofactor) widely present in prokaryotes, plants, and mammalian tissues, initially isolated from methylotrophic bacterial cultures. It is an anionic redox-cycling ortho-quinone.
PQQ not only serves as a prosthetic group for many enzymes, functioning to transfer electrons, protons, and chemical groups in enzymatic reactions, but also stimulates microbial growth, plant pollen germination, and promotes plant growth. Research indicates that PQQ-2Na is crucial for immune function and is an essential nutrient for mammals.
EINECS: 209-118-9
Product Categories: PQQ;nutrition supplement
특성
Appearance & Form: Solid, Pink to red
Storage Temperature: 2-8°C
Biological Source: fermentation/recombinant
Water Solubility: Water : 6.16 mg/mL (16.46 mM)
응용 분야
1. Health Supplements and Nutraceuticals (Primary Application):
Key Ingredient: Used as the active ingredient in commercially available health supplements, providing health support based on its various biological activities.
Primary Health Benefits:
Neuroprotection: Possesses nerve growth factor-inducing activity and has a certain effect on Parkinson's disease.
Organ Protection: Can prevent immune-mediated liver injury.
Cardiac and Mitochondrial Health: The overview mentions that PQQ itself has effects such as treating heart disease and maintaining mitochondrial function.
Immune Support: As an essential nutrient, it is important for immune function.
2. Basic and Biotechnology Research:
Enzymology Research: Used as a prosthetic group for various enzymes to study their functions in catalytic reactions.
Plant and Microbiology: Researching its promotive effects on microbial growth, plant pollen germination, and growth.
Immunology and Developmental Research: In vitro studies suggest that mouse pups born to and nursed by PQQ-deprived dams have compromised immune responses, alopecia, a hunched posture, and susceptibility to aortic aneurysms, providing a model for related research.
3. Potential Medical Application Directions (Based on Overview):
Potential for research in treating heart disease and neurological disorders.
Research for liver protection functions.
| 파일명 | 다운로드 |
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| COA PQQ 122628-50-6.pdf |
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