
1002-84-2


Pentadecanoic acid (C15:0) serves as an essential odd-chain saturated fatty acid that acts as a validated biomarker for dairy fat intake while delivering potent cardiometabolic protection through anti-inflammatory, anti-fibrotic, and mitochondrial-supporting mechanisms. It also functions as a leading anti-aging nutrient with mTOR-inhibitory activity that enhances antioxidant defenses, epigenetic regulation, immune balance, hepatic health, and cellular resilience against metabolic and age-related disorders.
Pentadecanoic acid is a high-purity (≥98%) white crystalline powder and a rare straight-chain odd-numbered saturated fatty acid naturally produced via rumen microbial fermentation, occurring at ~1.2% of total fatty acids in conventional cow milk fat (higher in organic milk) and representing the primary dietary source through butterfat and ruminant products. Unlike abundant even-chain saturated fatty acids historically linked to increased disease risk, C15:0 has emerged as a biologically essential nutrient with strong inverse associations to coronary heart disease, type 2 diabetes, and metabolic syndrome, while serving as a reliable plasma/RBC biomarker for dairy consumption and a cost-effective internal standard in lipid analysis. Recent groundbreaking cell-based, preclinical, and human supplementation studies (including direct comparisons to rapamycin) highlight its broad, clinically relevant activities: robust anti-inflammatory, anti-fibrotic, anti-cancer, and longevity-promoting effects; improved mitochondrial function, cell membrane stability, antioxidant capacity, and epigenetic control; plus mTOR inhibition, reduced anaemia and dyslipidaemia, and enhanced hepatic and immune resilience—establishing Pentadecanoic acid as a premier research-grade and nutraceutical ingredient for advanced formulations focused on healthy aging, cardiometabolic optimization, preventive metabolic health, and therapeutic innovation in chronic disease management.
EINECS: 213-693-1
Product Categories: Alkylcarboxylic Acids;Biochemistry;Higher Fatty Acids & Higher Alcohols;Monofunctional & alpha,omega-Bifunctional Alkanes;Monofunctional Alkanes;Saturated Higher Fatty Acids;C13 to C42+Fatty Acids;PA - PENFatty Acids;Fatty AcidsFA/FAME/Lipids/Steroids;Free Fatty Acids;Lipid Analytical Standards;NeatsAlphabetic;Other Lipid Related Products;P;Fatty Acids;Saturated fatty acids and derivatives;Straight chain fatty acids;Carbonyl Compounds;Carboxylic Acids
Melting point: 51-53 °C(lit.)
Boiling point: 257 °C100 mm Hg(lit.)
Density: 0.8423
Refractive index: 1.4292
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility: Soluble in ethanol.
Pka: 4.78±0.10
Form: Powder or Flakes
Color: White
Odor: waxy
Biological source: synthetic (organic)
Water Solubility: 12mg/L(20 ºC)
Stability: Stable. Combustible. Incompatible with bases, reducing agents, oxidizing agents.
LogP: 6.62
1.Dietary supplements and functional foods: incorporated to raise circulating C15:0 levels, support heart and metabolic health, reduce inflammation, and promote longevity.
2.Cardiometabolic and anti-aging research: applied to study protection against fibrosis, obesity, diabetes, liver disease, and age-related cellular decline.
3.Nutritional epidemiology and biomarker analysis: used as a gold-standard marker for dairy fat intake and associated disease risk assessment.
4.Pharmaceutical and hepatic/immune development: explored for anti-fibrotic, liver-protective, immune-modulating, and anticancer therapeutic strategies.
5.Laboratory and analytical chemistry: serves as an internal reference standard in fatty acid profiling and lipid metabolism investigations.
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