Spermidine

124-20-9

Spermidine

Spermidine•Anti-aging

Struktur:

CAS: 124-20-9

MF: C7H19N3

MW: 145.25

Synonyme

1,8-DIAMINO-4-AZAOCTANESPERMIDINE FREE BASESPERMIDINEOMEGA-AMINOBUTYL-OMEGA-AMINOPROPYLAMINEN1-(3-AMINOPROPYL)BUTANE-1,4-DIAMINEN-(3-AMINOPROPYL)-1,4-BUTANDIAMINEN-[3-AMINOPROPYL]-1,4-BUTANEDIAMINEN-(3-AMINOPROPYL)-1,4-DIAMINOBUTANE

Verwendung

Spermidine is primarily used as an important pharmaceutical intermediate, widely applied in drug synthesis. Concurrently, it is a key bioactive molecule capable of exerting various physiological effects, such as delaying aging and regulating cellular functions, by modulating processes like protein metabolism and autophagy.

Spezifikation

99%+

Beschreibung

Übersicht

Spermidine is a low molecular weight aliphatic polyamine containing three amino groups and is one of the natural polyamines present in all living organisms. In terms of physicochemical properties, it is a colorless transparent liquid, hygroscopic, and soluble in water, alcohol, and ether.

EINECS: 204-689-0

Product Categories: co-factor;124-20-9;Coronavirus;API

Eigenschaften

Appearance & Form: Liquid After Melting, Clear colorless，Ichtyal, ammoniacal

Melting Point: 23-25 °C

Boiling Point: 128-130 °C (14 mmHg)

Density (at 20 °C) / Specific Gravity: 1.00 g/mL / 0.925

Storage Temperature: room temp

Solubility: H2O: 1 M at 20 °C, clear, colorless

pH (25℃, 1M in H2O): 12.0-13.5

pKa: 10.53±0.19 (Predicted)

Biological Source: synthetic

Water Solubility: Miscible with water, ethanol and ether.

Sensitivity: Air Sensitive

Stability: Stable, but air-sensitive and very hygroscopic - store under argon. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.

Anwendungen

Based on its chemical properties and diverse biological activities, spermidine has well-defined and specific applications in several fields:

Pharmaceutical Chemistry: Serves as a key pharmaceutical intermediate for the synthesis of various drugs.

Neuroscience Research: Used as a research tool to explore its potential effects on neuroprotection, synaptic function, cognitive health, and related neurological disorders.

Biochemistry & Molecular Biology Research:

DNA/Protein Studies: Utilizes its property of binding and precipitating DNA for DNA purification and the purification of DNA-binding proteins.

Enzymology: Used to stimulate the activity of T4 polynucleotide kinase.

Signaling Pathway Research: Serves as an inhibitor of neuronal nitric oxide synthase (nNOS) for related signal transduction studies.

Plant Science & Agricultural Research: Investigates its role in regulating plant growth, development, and stress resistance, including delaying leaf senescence.

Aging & Longevity Research: As an important model molecule for exploring strategies to intervene in the aging process and related diseases by modulating autophagy and protein homeostasis.