NR-CL
23111-00-4
NR-CL
Nicotinamide Riboside Chloride (NR-CL) is primarily used as an efficient and safe NAD+ (Nicotinamide Adenine Dinucleotide) precursor to elevate intracellular NAD+ levels, thereby supporting cellular energy metabolism, mitochondrial health, and organismal anti-aging. Furthermore, it has obtained GRAS (Generally Recognized As Safe) status and can be directly used as a functional ingredient in dietary supplements and foods to provide vitamin B3 and confer additional health benefits.
概览
Nicotinamide Riboside Chloride, chemically named 3-Carbamoyl-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-pyridin-1-ium chloride, also known as 1-(β-D-Ribofuranosyl)nicotinamide chloride, is a crystalline, stable salt form of Nicotinamide Riboside (NR).
EINECS: 200-184-4
Product Categories: NMN;Food additive;API;1;23111-00-4
特点
Appearance & Form: White solid
Biological Source: milk
Storage Temperature: under inert gas (nitrogen or Argon) at 2-8°C
Solubility: Soluble to 100 mM in DMSO and to 100 mM in water
Water Solubility: 10mg/mL, clear, colorless
Stability: Hygroscopic
应用领域
Based on its core mechanism of elevating NAD+ and its GRAS safety profile, Nicotinamide Riboside Chloride is primarily applied in the following fields:
1. Dietary Supplements & Functional Foods (Core Application):
Healthy Aging & Anti-Aging: As a core ingredient in products designed to enhance cellular energy, support mitochondrial function, and activate sirtuin pathways for promoting healthy aging.
Metabolic Health: Used in supplement formulations aimed at supporting metabolic health, improving insulin sensitivity, and weight management.
Energy & Sports Performance: For developing products intended to boost physical energy, alleviate exercise fatigue, and promote recovery.
Neurological Health: As an ingredient in supplements supporting brain health, cognitive function, and neuroprotection.
2. Pharmaceutical R&D:
As a lead compound or active ingredient for investigating its potential in treating diseases associated with declining NAD+ levels, such as neurodegenerative disorders, metabolic syndrome, cardiovascular diseases, and certain myopathies.
3. Scientific Research:
As a standard tool molecule or interventional agent for studying NAD+ metabolism, mitochondrial biology, aging mechanisms, metabolic regulation, and neuroscience.
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